You can create a new Audience from anywhere in the Resonate platform by clicking Segmentation in the top navigation.
You can also create a new Audience from the Your Saved Audiences page by clicking the Create New Audience button at the top right of the page.
Both of these actions will bring you to the Audience Builder in Segmentation Center. On the left side of the page, you'll see the taxonomy in an accordion-style hierarchy. Navigate the taxonomy or use search to find and add attributes to your audience definition.