Are there attribute values that cannot be activated?

Yes, the following attribute values cannot be included in an audience for activation or engagement. This means audiences that contain these attributes cannot be activated or targeted as an audience for media delivery, and they cannot be included in a data append.  

1. Transgender Identity 
2. Sexual Orientation 
3. All appended 3rd party data. 
4. Low Sample Audiences (a great workout is to combine several attribute values in a single audience to get better sample).

Attributes that cannot be activated are flagged as such in the Audience Builder in Segmentation Center with an ! icon. 

3rd party appended data cannot be activated due to our contract with our 3rd party data provider.